陳佩君

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基本資料

  • 姓名：陳佩君

  • 職稱：副教授

  • 研究專長：生物統計、生物資訊、資料探勘與機器學習、貝氏統計

  • 授課領域：統計學、機率論、數理統計、線性代數

  • 聯絡電話：27321104#53305

  • 電子郵件：peichuncc@mail.ntue.edu.tw

 

個人介紹

學歷:

台灣大學 流行病學研究所 生物醫學統計組 博士

經歷:

國立臺北教育大學, 數學暨資訊教育學系,副教授教授, 2021/08~迄今

 

靜宜大學 資料科學暨大數據分析與應用學系, 副教授, 2017/08~2021/07

 

台灣大學公共衛生碩士學位學程, 專案助理教授, 2009/11~2010/07

 

台灣大學醫學卓越研究中心, 生物資訊暨生物統計核心實驗室, 博士後研究員, 2008/03~2009/10

 

個人著作與發表

A. 期刊論文

  • Chen, P. C., Huang, S. Y., Chen, W.J. and Hsiao, C. K. (2009) A new regularized least squares support vector regression for gene selection. BMC Bioinformatics 2009, 10:44.

  • Chen, P. C.*, Lee, K. Y., Lee, T. J., Lee, Y. J. and Huang, S. Y. (2009) Multiclass support vector classification via coding and regression. Neurocomputing, doi:10.1016/j.neucom.2009.11.005.

  • Wei, Y. C., Wen, S. H., Chen, P. C., Wang, C. H. and Hsiao, C. K.*, (2010) A simple Bayesian mixture model with a hybrid procedure for genome-wide association studies.  European Journal of Human Genetics, 18, 942–947, doi:10.1038/ejhg.2010.51.

  • Miaw, S. C., Chen, J. S., Hsieh, P. C., Liu, C. Y., Chung, M. H., Chen, P. C., Chang, M. L., Chen, F. L.,  Kung, J. T., and Wang, L. F.* (2010) CD44-deficient mice do not exhibit impairment of epidermal Langerhans cell migration to lymph nodes after epicutaneous sensitization with protein. Journal of Investigative Dermatology, 130, 2674-2677, doi:10.1038/jid.2010.170.

  • Lu, T. P., Tsai, M. H., Lee, J. M., Hsu, C. P., Chen, P. C., Lin, C. W., Shih, J. Y., Yang, P. C., Hsiao, C. K., Lai, L. C., and Chuang, E. Y.* (2010) Identification of a novel biomarker, SEMA5A, for non-small cell lung carcinoma in nonsmoking women. Cancer Epidemiology Biomarkers & Prevention, 19 (10):2590-7.

  • Hsiao, C. K.*, Chen, P. C. and Kao, W. H., (2011) Bayesian random effects for inter-rater and test-retest reliability with nested clinical observations. Journal of Clinical Epidemiology, V.64, issue 7, 808-814.

  • Lu, T. P., Lai, L. C., Tsai, M. S., Chen, P. C., Hsu, P. C., Lee, J. M., Hsiao, C. K. and Chuang, E. Y.*, (2011) Integrated analyses of copy number variations and gene expression in lung adenocarcinoma. PLos One, V.6, issue 9, e24829.

  • Chen, Lee H., Kuo, W. H., Tsai, M. H., Chen, P. C., Hsiao, C. K., Chuang, E. Y., Hsieh, F. J., Lai, L. C.*, Chang, K. J., (2011) Identification of prognostic genes for recurrent risk prediction in triple negative breast cancer patients in Taiwan. PLos One, V.6, issue 11, e28222.

  • Lin, J. Y., Chen, J. S., Hsu, C. J., Miaw, S. C., Liu, C. Y., Lee, S. J., Chen, P. C., Wang, L. F.* (2012) Epicutaneous sensitization with protein antigen induces Th9 Cells. Journal of Investigative Dermatology, 132, 739–741; doi:10.1038/jid.2011.382.

  • Chen, P. C., Chen, Y. C., Lai, L. C., Tsai, M. H., Chen, S. K., Yang, P. W., Chang, K. J., Lee, Y. C., Hsiao, C. K., Lee, J. M., and Chuang, E. Y.*, (2012) Use of germline polymorphisms in predicting concurrent chemoradiotherapy response in esophageal cancer. International Journal of Radiation Oncology, Biology & Physics, 82 (5), 1996-2003.

  • Chen, P. C., Lu, T. P., Chang, J. C., Lai, L. C., Tsai, M. H., Hsiao, C. K., and Chuang, E. Y. *, (2013) Concurrent analysis of copy number variation and gene expression: application in paired non-smoking female lung cancer patients. International Journal of Data Mining and Bioinformatics, 8 (1), 92-104.

  • Lai, L. C., Tsai, M. H., Chen, P. C., Chen, H. L., Hsiao, J. H., Chen, S. K., Lu, T. P., Lee, J. M., Hsu, C. P., Hsiao, C. K., and Chuang, E. Y*, (2014) SNP rs10248565 in HDAC9 as a novel genomic aberration biomarker of lung adenocarcinoma in non-smoking women. Journal of Biomedical Science.2014, 21:24, DOI: 10.1186/1423-0127-21-24

  • Hsu, Y. S., Chen, P. C., Lee, M. Y., and Wu, C. H*., (2020) Applications of an Extended Geometric Brownian Motion Degradation Model. Communications in Statistics – Theory and Methods. https://doi.org/10.1080/03610926.2020.1764039

  • Hsu, Y. S., Chen, P. C., and Wu, C. H*., (2021) The optimal limit prices of limit orders under an extended geometric Brownian motion with bankruptcy risk. Mathematics (Special Issues).

  • Chen, Y. J., Chen, I. C., Lin, H. J., Lin, Y. C., Chang, J. C., Chen, Y. M., Hsiao, T. H., Chen, P. C.*, Lin, C. H.*, (2021) Association of ABCG2 rs2231142 allele and BMI with hyperuricemia in an east Asian population. Frontiers in Genetics,  https://doi.org/10.3389/fgene.2021.709887

  •  Chen, I. C., Chen, Y. J., Chen, Y. M., Lin, H. J., Lin, Y. C., Chagn, J. C., Chen, P. C.* and Lin, C. H.*, (2021) Interaction of Alcohol Consumption and ABCG2 rs2231142 Variant Contributes to Hyperuricemia in a Taiwanese Population. Journal of Personalized Medicine. https://doi.org/10.3390/jpm11111158

  • Hsu, Y. S., Chen, P. C. and Wu, C. H.*, (2022) Double-barrier option pricing equations under extended geometric Brownian motion with bankruptcy risk. Statistics & Probability Letters. V. 184. https://doi.org/10.1016/j.spl.2022.109383.

 

B. 研討會論文

 

  • Wang, P. C., Lai, L. C. Tsai, M.. H., Chuang, E. Y., Kao, C. Y., Chen, P. C., (2012) An algorithm for gene-gene interaction via deviance of independence, October 13-16, 2012, in Jeju Island, Korea. (poster)

  • Lu, T. P., Chen, P. C., Lai, L. C., Tsai, M. H., Hsiao, C. K., and Chuang, E. Y. (2010) Concurrent Analysis of Copy Number Variations and Expression Profiles to Identify Genes Associated with Tumorigenesis and Survival Outcome in Lung Adenocarcinoma. IEEE International Conference on Bioinformatics & Biomedicine, December 18-21, 2010, in Hong Kong.

  • Lu, R. Y., Hsiao, C. K., Tsai, M. H., Chen, P. C., Chuang, E. Y., and Lai, L. C. (2010) Utilizing Cox Regression Model to Assess the Relations between Predefined Gene Sets and the Survival Outcome of Lung Adenocarcinoma. IEEE International Conference on Bioinformatics & Biomedicine, December 18-21, 2010, in Hong Kong.

  • Chang, J. C., Lu, T. P., Lai, L. C., Tsai, M. H., Hsiao, C. K., Chuang, E. Y., and Chen, P. C. (2010)  Concurrent Analysis of Copy Number Variation and Gene Expression: Application in Paired Non-Smoking Female Lung Cancer Patients. IEEE International Conference on Bioinformatics & Biomedicine, December 18-21, 2010, in Hong Kong.

  • Chen, Lee, Lai, L. C., Hsiao, C. K., Chen, P. C., Tsai, M. H., Kuo, W. H., Chang, K. J., and Chuang, E. Y. (2010) Comparison of Triple Negative Breast Cancer between Asian and Western Data Sets. IEEE International Conference on Bioinformatics & Biomedicine, December 18-21, 2010, in Hong Kong. (workshop)

  • Chen, P. C., Chen, Y. C., Lai, L. C., Tsai, M. H., Chen, S. K., Yang, P. W., Chang, K. J., Lee, Y. C., Lee, J. M., and Chuang, E. Y. (2009) Two-stage genome-wide association study for CCRT response in esophageal cancer. American Association for Cancer Research 100th Annual Meeting, April 18-22, 2009, in Denver, USA. (poster)

  • Chen, P. C, Huang, S. Y., Chen, W.J., and Hsiao, C. K. (2008) A new support vector regression approach to gene selection. Joint Statistical Meetings of the American Statistical Association, August 3-7, 2008, in Denver, USA. (Invited)

  • Chen, P. C, Huang, S. Y., Chen, W.J., and Hsiao, C. K. (2008) A new support vector regression approach to gene selection. Workshop on statistical methodology on microarray data. Invited speaker. Taipei, Taiwan.

 

C. 專利

 

  • 預測食道癌病患對於化學暨放射線療法之反應的方法及套組，台灣，中華民國發明專利第098135448號 ，2009/10/20 - 2029/10/19。
  • BIOMARKERS FOR PREDICTING RESPONSE OF ESOPHAGEAL CANCER PATIENT TO CHEMORADIOTHERAPY, United States, US 8286562 B2, 2009/10/20 - 2029/10/19.

國科會計畫

  • 100    結合拷貝數、甲基化資料與基因表現量之整合性分析方法

  • 101   結合各基因體平台之整合性分析方法

  • 103  多重線性邏輯斯迴歸及其應用

  • 104  利用高斯連結模式分析多變量邏輯斯迴歸之貝氏統計推論